• Probiotic 60 Billion CFU supplement bottle by Dear Apothecary, 60 capsules
  • Probiotic benefits graphic: digestive health, immune support, gut-brain connection, nutrient absorption, daily energy, daily regularity
  • Probiotic 60 Billion CFU supplement facts: 4-strain blend with MAKTREK bypass technology, 2 capsules per serving
  • Probiotic 60 Billion CFU
  • Probiotic 60 Billion CFU

4.8 ★★★★★ 2,184 Reviews

POTENCY · PROTECTION · DELIVERY

Probiotic 60 Billion CFU


Regular price $39.00
$39.00 -20%
Sale price
Regular price
$49.00
Sale Sold out

Back in Stock · High Demand

01
LESS BLOATING & BETTER DIGESTION

4 researched strains support a balanced, comfortable gut.*

02
SURVIVES STOMACH ACID

MAKTREK Bi-Pass delivers live bacteria past stomach acid.*

03
GUT MICROBIOME RECOVERY

60 Billion CFU + FOS prebiotic fuel for microbiome rebuilding.*


60-day risk-free guarantee. Free US shipping $100+.

Ingredients
Potency 60 Billion CFU, 4 clinically-studied strains
Strains L. Acidophilus (La-14), B. Lactis (Bl-04), L. Plantarum (Lp-115), L. Paracasei (Lpc-37)
Delivery MAKTREK® Bi-Pass Technology protects strains through stomach acid
Quality Standards
Delivery Ships out next business day. Free insured shipping on $100+.
Quality Made in USA. GMP-Certified. 3rd-Party Tested.
Standards Non-GMO. Keto-Friendly. Gluten-Free. No Artificial Fillers.
Guarantee 60-Day Money-Back.

Bundle Your Supply

Probiotic benefits build with 90+ days of consistent use. Discounts apply automatically.

3 Bottles
90 Day SupplySave 25%

3 Bottles Probiotic 60B

$87.75$117$29/bottle
6 Bottles
180 Day SupplySave 35%

6 Bottles Probiotic 60B

$152.10$234$25/bottle
Probiotic 60 Billion CFU supplement bottle by Dear Apothecary, 60 capsules
Regular price $39.00
$39.00 -20%
Sale price
Regular price
$49.00
GQ Vogue Forbes Well+Good WWD GQ Vogue Forbes Well+Good WWD GQ Vogue Forbes Well+Good WWD

How It Works

The Probiotic difference: Benefits that build over time.

60 billion CFU across 4 clinically-studied strains, delivered with MAKTREK® Bi-Pass technology. Self-reported results from verified buyers after 60 days of daily use.

Digestion

Microbiome balance

87%

Less bloating, steadier rhythm

Weeks 1–2

Strains colonize the gut and crowd out less beneficial bacteria

Immune

Gut-immune axis

81%

Stronger seasonal immunity

Weeks 2–4

70% of immune cells live in the gut and respond to microbial signaling

Mood

Gut-brain axis

74%

More even daily mood

Weeks 4–8

Gut bacteria produce 90% of the body's serotonin precursors

Formula

4 strains, MAKTREK delivery, FOS fuel

60 billion CFU across four clinically researched strains, protected by MAKTREK Bi-Pass technology and fed by FOS prebiotic fiber. A focused formula at meaningful doses, not 20 strains spread thin. Delivery and dose are what make a probiotic work.

Four clinically researched strains at concentrations that match published research. More strains is not better, strains compete for resources, so a focused 4-strain formula at meaningful doses outperforms a 20-strain blend at trace amounts.

  • L. AcidophilusLa-14 strain
  • B. LactisBl-04 strain
  • L. PlantarumLp-115 strain
  • L. ParacaseiLpc-37 strain
  • Total60 Billion CFU per serving

MAKTREK is a patented Bi-Pass technology that shields probiotic bacteria from stomach acid. Up to 96% of unprotected probiotic bacteria are destroyed before reaching the intestines. MAKTREK creates a protective barrier so live bacteria reach the lower GI tract where they colonize.

  • MAKTREKPatented Bi-Pass technology
  • FunctionStomach acid protection

FOS (fructooligosaccharide) is a prebiotic fiber that feeds probiotic bacteria once they reach the gut. Most probiotic formulas skip this step. Complex Marine Polysaccharide adds further prebiotic and matrix support. Together they help the strains establish faster and last longer.

  • Fructooligosaccharide20mg · prebiotic fiber
  • Marine Polysaccharide50mg · prebiotic support
Total per serving 60B CFU + prebiotics

How to use

Dose 2 capsules daily
Timing Anytime, with or without food
With antibiotics Space 2+ hours apart
Storage Shelf-stable, no fridge

Quality standards

Potency 60 Billion CFU, 4 strains
Delivery MAKTREK Bi-Pass + FOS
Manufacturing GMP certified, made in USA
Testing 3rd-party tested per batch

Verified buyer experiences.

4.8 ★★★★★

Based on 2,184 verified reviews

5
83%
4
13%
3
2%
2
1%
1
1%
Ashley M.Texas
Verified buyer
★★★★★

Dealt with bloating after every meal for years. Tried yogurt, kombucha, fiber supplements. Nothing consistent. Started this probiotic and within about 8 days the bloating was noticeably less. Two months in and it's basically gone. The MAKTREK delivery is clearly doing something the others didn't.

05/14/26
Helpful?
James W.Connecticut
Verified buyer
★★★★★

Had to do a 10-day course of antibiotics and my gut was wrecked. Started this the day after finishing. Digestion was back to normal within two weeks instead of the usual month of discomfort. My GI doctor said the strain diversity probably helped the microbiome rebuild.

04/26/26
Helpful?
Vanessa C.New York
Verified buyer
★★★★★

Travel for work three weeks a month. Every probiotic I'd tried needed to stay cold, which meant I skipped it on the road. This one is shelf-stable. I keep a bottle in my carry-on. That consistency alone made a bigger difference than switching brands ever did.

04/09/26
Helpful?
Daniel M.Oregon
Verified buyer
★★★★★

Compare probiotic labels before buying. Most brands list 15 to 20 strains with no CFU breakdown, which usually means trace amounts of each. This one names 4 researched strains, La-14, Bl-04, Lp-115, Lpc-37, at 60 billion CFU total. Focused and honest. Three months in and digestion is the steadiest it's been.

03/24/26
Helpful?
Susan B.Pennsylvania
Verified buyer
★★★★

First few days my digestion felt a little off as my gut adjusted. Read that this is normal as the microbiome shifts. By the end of week one it settled, and by week three the regularity and comfort were clearly better. Worth pushing through the short adjustment period.

03/07/26
Helpful?
Karen H.Florida
Verified buyer
★★★★★

Digestion had been unpredictable for years. Some days fine, some days not. Started this and around week 2 things became consistent in a way they hadn't been in a long time. The FOS prebiotic feeding the strains seems to be the part most other probiotics leave out.

02/19/26
Helpful?
Margaret K.Massachusetts
Verified buyer
★★★★★

Gut got more sensitive as I aged. Foods I used to handle fine started causing discomfort. Started this 10 weeks ago. The day-to-day gut comfort has noticeably improved and I'm less reactive to meals. The 60 billion CFU dose is the right level of support.

02/03/26
Helpful?
Anthony R.New York
Verified buyer
★★★★★

Tried refrigerated probiotics before and always forgot them, or they sat in a hotel mini-fridge and got left behind. Shelf-stable means it lives on my counter next to the coffee and I actually take it every day. Consistency is what made the digestion improvement stick.

01/18/26
Helpful?
Marcus W.Texas
Verified buyer
★★★★★

Two capsules every morning for six months now. Bloating is a non-issue. Digestion is steady and predictable. Gut comfort holds even when I eat out or travel. A balanced microbiome takes consistency and this is easy to stay consistent with. Part of my routine for good.

01/02/26
Helpful?
Linda V.California
Verified buyer
★★★★★

IBS for a decade. Tried every probiotic on the market. This is the first one that actually held. Symptoms still flare on stress weeks but the baseline is steadier. Six weeks in. Won't go back to the others.

12/16/25
Helpful?
Tom J.Washington
Verified buyer
★★★★★

Read the label first. Most probiotics list 20 strains and you have no idea how much of each. This one names four strains with the CFU count and the prebiotic spelled out. Bought because of the label clarity. Stayed because the digestion improved.

11/30/25
Helpful?
Brandon K.Illinois
Verified buyer
★★★★★

Original at week 2: Mild gas the first few days. Settled. Digestion maybe slightly better, hard to call.

EDIT 3 months in: Glad I stuck with it. Bloating after big meals is basically gone. Regularity is steady. The MAKTREK protection plus the prebiotic is the combo. Bumping from 3 to 5 stars.

11/14/25
Helpful?
Hannah G.Colorado
Verified buyer
★★★★★

Skin started clearing around week 5 which I wasn't expecting. The gut and skin connection is real. Started this for bloating, got skin clearing too. The strain diversity plus the prebiotic feeding them must be the work happening underneath.

10/29/25
Helpful?
Greg P.Ohio
Verified buyer
★★★★

Working. Bloating is down, regularity is steady. The adjustment week was uncomfortable, lots of gas. Pushed through and it settled. Knocking a star for the rough first few days even though that's apparently normal.

10/13/25
Helpful?
Sarah K.Minnesota
Verified buyer
★★★★★

Doctor recommended a quality probiotic after my last GI workup. Looked at three brands and this one had the strain transparency I wanted. Three months in and my last appointment showed real improvement. Doctor approved the routine.

09/27/25
Helpful?
Jacob T.Virginia
Verified buyer
★★★★★

Endurance training puts stress on the gut. GI issues during long runs were ruining race days. Started this and the gut held through a half marathon. The microbiome support translates directly to athletic performance for me.

09/11/25
Helpful?
Olivia B.Connecticut
Verified buyer
★★★★★

New mom and my gut got weird after pregnancy. Doctor cleared this for post-nursing. Bloating eased within a few weeks. Energy improved alongside. The whole-system effect of a balanced gut is real.

08/26/25
Helpful?
Kevin M.Indiana
Verified buyer
★★★★★

Quit my old refrigerated probiotic because I'd forget it on travel weeks. Shelf stable changed everything. Take it daily now. Consistency was the missing piece. Three months in and I'd recommend without hesitation.

08/10/25
Helpful?
Ahmad B.Georgia
Verified buyer
★★★★★

Lactose intolerant. The dairy issues used to be brutal even with the lactose pills. After 6 weeks on this the reactions are noticeably milder. Still avoid heavy dairy but the occasional slice of cheese isn't a disaster anymore.

07/25/25
Helpful?
Christine F.Wisconsin
Verified buyer
★★★★

Solid product. Digestion is better, bloating is down. The price is the only knock for me, subscription brought it down a bit but it adds up at 2 capsules a day. Quality is there, just expensive.

07/09/25
Helpful?
Diego R.Nevada
Verified buyer
★★★★★

Husband and I both take it. Different gut issues, same formula works for both. He's the acid reflux, I'm the bloating. Both noticing improvement. One bottle covers two of us a month.

06/23/25
Helpful?
Patricia O.Tennessee
Verified buyer
★★★★★

Acid reflux had been creeping in for years. Doctor mentioned the gut microbiome connection. Three months on this and the reflux episodes are way down. Diet matters too but the probiotic was the piece I'd been missing.

06/07/25
Helpful?
Carlos N.Missouri
Verified buyer
★★★★★

12 years in food service, eating at weird hours and weird food. Gut was a wreck. Started this and within two months things normalized. The 60 billion CFU dose is what the cheaper probiotics couldn't deliver.

05/21/25
Helpful?
Heather J.Michigan
Verified buyer
★★★

Finished a bottle. Digestion maybe slightly steadier, hard to tell. No clear shift in bloating or regularity. Quality of the product looks solid, ingredients look right. Just didn't get the dramatic change others describe. My gut might already be in decent shape. Open to retesting after some diet changes.

05/05/25
Helpful?
Linda S.Kentucky
Verified buyer
★★★★★

Daily ritual now. Two capsules with breakfast. Bloating gone, regularity steady, mood is better as a bonus. The gut and brain connection shows up here too. Eight weeks consistent and not going back.

04/19/25
Helpful?

Questions?
We're here to help.

Many users notice less bloating and steadier digestion within 1 to 2 weeks. Microbiome balance builds over 4 to 8 weeks as the strains reach stable populations. A balanced gut is a long-term foundation, so the clearest results show with consistent daily use over 90 days and beyond.

MAKTREK is a patented Bi-Pass technology that shields probiotic bacteria from stomach acid. Up to 96% of unprotected probiotic bacteria are destroyed before reaching the intestines, which is where they need to colonize. MAKTREK creates a protective barrier that delivers live bacteria past stomach acid into the lower GI tract.

More strains does not mean better results. Strains compete with each other for resources, so a 20-strain blend at trace amounts often performs worse than a focused formula at meaningful doses. This formula uses 4 clinically researched strains (La-14, Bl-04, Lp-115, Lpc-37) at concentrations that match published research, rather than spreading the dose thin across many strains.

No. The gut already contains trillions of bacteria, so 60 billion CFU is a clinically relevant dose for meaningful colonization. Most drugstore probiotics ship 1 to 10 billion CFU, which is below the threshold where measurable effects typically appear in research.

No. This formula is shelf-stable. The strains are selected and processed for room-temperature stability, and MAKTREK protects bacterial viability. Store in a cool, dry place. Shelf stability makes it easy to travel with and easy to stay consistent with day to day.

Yes, but space them at least 2 hours apart. Antibiotics kill bacteria indiscriminately, so taking probiotics at the same time reduces their effectiveness. Many GI specialists recommend taking probiotics during or immediately after an antibiotic course to support microbiome recovery. Talk to your provider about your specific situation.

FOS (fructooligosaccharide) is a prebiotic fiber that feeds probiotic bacteria. Most probiotic formulas omit this step. Including FOS gives the bacteria fuel to thrive once they reach the gut, which supports faster establishment and longer-lasting effects. The Complex Marine Polysaccharide adds further prebiotic support.

Two capsules daily, with or without food. MAKTREK protects the strains regardless of stomach contents, so timing is flexible. Daily consistency matters more than the exact hour. Pick a time you'll remember and stick with it.

Probiotics are generally well-tolerated alongside most supplements and medications. If you are severely immunocompromised, are undergoing chemotherapy, or have a serious underlying medical condition, talk to your healthcare provider before starting a probiotic, since live bacteria warrant medical guidance in those situations.

Most users tolerate this formula well. Some experience mild digestive changes, gas, or shifts in regularity in the first few days as the microbiome adjusts. This typically settles within a week. Stop use and talk to your provider if discomfort persists or you experience unusual symptoms.

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