Berberine Bark & Root HCl
AMPK Activation
Triggers the same metabolic pathway as exercise and fasting.*
Glucose & Lipid Support
Helps regulate blood sugar and cholesterol metabolism.*
Dual-Source Extract
Bark + root for a broader spectrum of active alkaloids.*
INGREDIENTS
Berberine HCl · 1200mg
Dual-source extract from Berberis aristata bark + root for a broader spectrum of active alkaloids.*
WHY DUAL-SOURCE?
Single-source berberine misses half the picture. Our bark + root extract delivers complementary alkaloids for better absorption and stronger metabolic activity.*
Quality Standards
Delivery
Ships Out Next Business Day · Free Insured Shipping on $100+
Quality
Made in USA · GMP-Certified · 3rd-Party Tested
Standards
Non-GMO · Keto-Friendly · Gluten-Free · No Artificial Fillers
Guarantee
60-Day Money-Back Guarantee
Your Metabolic Protocol
Berberine benefits compound with 90+ days of consistent use
3 Bottles
6 Bottles
60-Day Money-Back Guarantee · Free Shipping on Orders $100+
6 Core Benefits
Berberine activates the same metabolic pathways as exercise and fasting—without the sweat.*
Blood Sugar Support
Metabolic Activation
Lipid Balance
Weight Management
Gut Health
Cellular Energy
01
Blood Sugar Support
AMPK Pathway • Glucose Uptake
Berberine enhances insulin sensitivity and promotes glucose uptake into cells. Studies show it can support healthy blood sugar levels already within normal range—comparable to some pharmaceutical interventions.*
30+ Clinical StudiesThe Science
AMPK
metabolic master switch
Berberine activates AMPK—the same pathway triggered by exercise and fasting. This regulates glucose uptake, fat metabolism, and cellular energy.*
30+
Clinical Studies
1,200mg
Clinical Dose
2x
Source Extracts
4-8wks
To See Results
*Based on published research on berberine and metabolic health
What's Inside
Dual-Source, Clinical Dose
1,200mg
Berberine HCl
Dual-source extract from Berberis aristata bark + root for a broader spectrum of active alkaloids. Activates AMPK to support glucose metabolism, lipid balance, and cellular energy.*
Quality Promise
Purity & Potency Guaranteed
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GMP Certified Facility
Manufactured in a facility that meets FDA Good Manufacturing Practice standards.
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Third-Party Tested
Every batch tested by independent labs for purity and potency.
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Heavy Metals Screened
Tested for lead, mercury, arsenic, and cadmium contamination.
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Made in the USA
Manufactured in the United States with globally sourced ingredients.
How to Use
Take 2 Capsules Daily
1
Split Your Dose
1 capsule with breakfast, 1 with dinner for sustained activity.
2
Take With Meals
Food improves absorption and maintains steady blood levels.
3
Allow 4-8 Weeks
Metabolic benefits build over time. Most see changes by week 8.*
Common Questions
Frequently Asked Questions
Is berberine really as effective as metformin?
Multiple studies have shown berberine can support healthy blood sugar levels comparably to metformin. However, berberine is a supplement, not a medication. If you're currently taking metformin or other blood sugar medications, consult your healthcare provider before adding berberine—do not replace prescribed medications without medical guidance.
Why split the dose instead of taking it all at once?
Berberine has a short half-life (about 4-5 hours), meaning it clears your system relatively quickly. Splitting your dose—one capsule with breakfast, one with dinner—maintains more consistent blood levels throughout the day for sustained AMPK activation.
What does "dual-source" mean?
We extract berberine from both the bark AND root of Berberis aristata (Indian barberry). Different plant parts contain slightly different alkaloid profiles. Combining both provides a broader spectrum of active compounds compared to single-source extracts.
Can I take berberine with other supplements?
Berberine pairs well with most supplements. It's often stacked with milk thistle for liver support or omega-3s for cardiovascular health. However, avoid taking it at the same time as medications—berberine can affect how your liver processes certain drugs. Space them 2-3 hours apart.
Will I experience any side effects?
Some people experience mild GI discomfort (cramping, diarrhea, or constipation) in the first week, especially at higher doses. Taking berberine with food significantly reduces this. If symptoms persist, try starting with one capsule daily and gradually increasing to the full dose.
Who should NOT take berberine?
Do not use if pregnant or nursing—berberine can cross the placenta. Avoid if taking blood thinners, immunosuppressants, or medications metabolized by the liver (CYP450 pathway). If you have low blood pressure or take blood sugar/cholesterol medications, consult your healthcare provider first.
