• NAD+ Longevity cellular renewal supplement bottle by Dear Apothecary, 60 capsules
  • NAD+ Longevity benefits graphic: cellular energy, healthy aging, mental clarity, metabolism support, DNA repair, overall vitality
  • NAD+ Longevity supplement facts: Nicotinamide Riboside 500mg, Trans-Resveratrol 150mg, Quercetin, Fenugreek, 2 capsules per serving
  • NAD+ Longevity
  • Woman taking a NAD+ Longevity capsule outdoors on a mountain trail

4.8 ★★★★★ 5,142 Reviews

FUEL · ACTIVATE · ABSORB

NAD+ Longevity


Regular price $59.00
$59.00 -25%
Sale price
Regular price
$79.00
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Back in Stock · Sold Out 3 Times

"The only NAD+ supplement with clinical dosing AND the activators included. Everything else is incomplete."
David L., Colorado Verified Buyer
01
RESTORE CELLULAR ENERGY

500mg Nicotinamide Riboside, the clinical dose used in published NAD+ research.*

02
SUPPORT HEALTHY AGING

Trans-Resveratrol activates sirtuins, the proteins that drive cellular repair.*

03
SHARPER MENTAL CLARITY

Quercetin and Galactomannans complete the system, not just the precursor.*


60-day risk-free guarantee. Free US shipping $100+.

Ingredients
NAD+ Precursor Nicotinamide Riboside Chloride 500mg (clinical dose)
Sirtuin Trans-Resveratrol 150mg (from Japanese Knotweed)
Senolytic Quercetin 50mg (targets senescent cell pathways)
Absorption Galactomannans 10mg (fenugreek-derived fiber)
Quality Standards
Delivery Ships out next business day. Free insured shipping on $100+.
Quality Made in USA. GMP-Certified. 3rd-Party Tested.
Standards Non-GMO. Keto-Friendly. Gluten-Free. No Artificial Fillers.
Guarantee 60-Day Money-Back.

Bundle Your Supply

Longevity benefits build with 90+ days of consistent use. Discounts apply automatically.

3 Bottles
90 Day SupplySave 25%

3 Bottles NAD+ Longevity

$132.75$177$44/bottle
6 Bottles
180 Day SupplySave 35%

6 Bottles NAD+ Longevity

$230.10$354$38/bottle
NAD+ Longevity cellular renewal supplement bottle by Dear Apothecary, 60 capsules
Regular price $59.00
$59.00 -25%
Sale price
Regular price
$79.00
GQ Vogue Forbes Well+Good WWD GQ Vogue Forbes Well+Good WWD GQ Vogue Forbes Well+Good WWD

How It Works

The NAD+ difference: Benefits that build over time.

500mg Nicotinamide Riboside plus Trans-Resveratrol, Quercetin, and Galactomannans activate three longevity mechanisms. Self-reported results from verified buyers after 90 days of daily use.

Cellular Energy

NAD+ precursor

82%

More steady daily energy

Weeks 2–4

NR raises NAD+ levels, fueling mitochondrial energy production

Sirtuin Activation

Trans-resveratrol

78%

Healthier biological markers

Weeks 4–8

Resveratrol activates sirtuins so NAD+ engages longevity pathways

Senolytic Defense

Quercetin

71%

Improved recovery and resilience

Weeks 8–12

Quercetin targets senescent cell pathways for healthier aging

Formula

A complete NAD+ system, not just a precursor.

NAD+ formula
01 Active Compounds 710 mg
  • Nicotinamide RibosideNAD+ precursor · 500mg
  • Trans-ResveratrolSirtuin activator · 150mg
  • QuercetinSenolytic compound · 50mg
  • GalactomannansAbsorption enhancer · 10mg
500mg NR
Trans-Resveratrol
Quercetin + Galactomannans
GMP Certified
Made in USA
3rd-Party Tested

Take 2 capsules in the morning with breakfast that includes some fat. Resveratrol and quercetin absorb better with fat. Allow 2 to 4 weeks for energy, 4 to 8 weeks for clarity.

Timeline

What to expect

Energy and recovery shift first. Cognitive and cellular benefits compound over 8 to 12 weeks of daily use.

Weeks 1–2

NAD+ levels rise

NR begins converting to NAD+ inside cells. Steadier mornings start to show up.

Weeks 2–4

Energy and recovery

Daytime energy steadies. Workout recovery tightens up. Less afternoon fatigue.

Weeks 4–8

Mental clarity

Brain fog lifts. Sharper focus, faster recall. Sirtuin activity compounds.

Day 90+

Cellular vitality

Sustained NAD+ levels support healthy aging at the cellular level with daily use.

Verified buyer experiences.

4.8 ★★★★★

Based on 5,142 verified reviews

5
84%
4
11%
3
3%
2
1%
1
1%
Mark D.Texas
Verified buyer
★★★★★

A bit of background. I had been on a much pricier NAD precursor for about a year and felt a real difference from it. Money got tight and I cancelled. After two weeks I missed the energy boost so I tried two cheaper options from Amazon and was not impressed. Ordered this one almost as an afterthought. It feels essentially the same as the expensive bottle I was on for a year. Not a placebo, the other budget options did nothing for me and I really wanted them to work. For reference I am a 46 year old guy with a desk job. The price difference adds up over a year.

Helpful?
Amanda B.California
Verified buyer
★★★★★

I honestly cant believe how well these worked for me. A month in I am hardly ever tired, my head feels clearer, my energy is steady through the day, and I just feel happier overall. I didnt think a supplement like this would actually do anything for me so I was caught off guard by the difference.

Helpful?
Karen P.Florida
Verified buyer
★★★★★

This has genuinely changed my day to day. I have energy, sleep better, and went from popping a lot of ibuprofen for joint aches to barely needing any. Im eating better because I feel better. Started at two capsules in the morning and bumped to three about a month in. Almost two months in and I plan to stay on it.

Helpful?
Kristen H.Colorado
Verified buyer
★★

I was on the full dose for three weeks and started having really intense, unsettling dreams almost every night for no other reason I could think of. I dropped to half the dose and the dreams stopped. Tried the full dose again and the dreams came right back. Never noticed any real benefits and the lost sleep wasnt worth it. I take one every few days now just to use up the bottle.

Helpful?
Eric S.Washington
Verified buyer
★★★★

A few weeks in and Im happy with it overall. I bought it for energy and focus and there is a real difference there. It is on the strong side though. The full dose was a bit much for me at first. I would start with one capsule a day and work up. Not a miracle pill but combined with decent sleep and exercise it is helping me.

Helpful?
Daniel K.New York
Verified buyer
★★★★★

Im in this one for the long game. NAD supplementation is about supporting cellular function over time, not chasing a buzz. The label tells you exactly whats in it and at what dose, no proprietary blends hiding amounts. The bottle lasts a while which makes it easier to stay consistent. Good dose, fair price, part of my daily protocol.

Helpful?
Toure T.Georgia
Verified buyer
★★★★

This works well if you dont overdo it. Taking a capsule every day I got facial flushing and some redness. Backed off to three times a week and that works better. It can replace my morning coffee on the days I take it.

Helpful?
Susan R.Oregon
Verified buyer
★★★★★

A week in and I felt an energy lift on the very first day with two capsules. I am a small woman so I have backed off to one a day with a full glass of water and that feels right. I also do morning walks and use a light therapy lamp at my desk but this is what pushed me over into actually feeling good in the mornings.

Helpful?
Robert M.Ohio
Verified buyer
★★★

I ordered this hoping for an energy lift or some other noticeable benefit. Two capsules every morning with water for a couple of months and I cant tell a difference. Capsules are easy to swallow and no negative effects, just no positive ones either. Your experience may be different.

Helpful?
Angela N.Pennsylvania
Verified buyer
★★★★★

My oncologist okayed this for me to try alongside my chemo treatments to help with the fatigue. It has made the bad days less wiped out and Im grateful for that. Always check with your own care team but this has been a part of getting me through.

Helpful?
Pablo A.Arizona
Verified buyer
★★★★★

Real difference for me. I take two capsules in the morning with my B complex and a protein shake. I get a few hours of steady energy, less stress through the day, and it helps my workouts. It is also taking the edge off snacking which is helping me with weight loss. Sticking with this combination for a while.

Helpful?
Patrick C.Illinois
Verified buyer
★★★★★

There is some debate online about whether this kind of supplement can really reach the mitochondria but somehow this one does work for me. I have tried a few of the more expensive precursor options and this one delivers a similar lift at a much better price.

Helpful?
Sara T.Minnesota
Verified buyer
★★★★★

First time trying this brand and I am pleasantly surprised. No digestive issues and I have more energy and a better mood. I will absolutely buy it again.

Helpful?
Jessica K.North Carolina
Verified buyer
★★★★

I felt good on this overall but it slowed my digestion noticeably. I am usually pretty regular and on this I was only going once a day instead of my normal pattern. I took a few days off, got back to normal, then tried it again and the same thing happened. Outside of that I liked how it made me feel.

Helpful?
Allison C.Virginia
Verified buyer
★★★★★

This has helped my sleep dramatically. I take it in the morning and I am out the moment my head hits the pillow at night. Did not expect that to be the main benefit but Im not complaining.

Helpful?
Cheryl B.Tennessee
Verified buyer
★★★★★

I cant tell you exactly what this is doing inside me but I can say I have had more energy. I also lost a bit of weight in the last month so I cant attribute that to one thing. A month in, no negatives, possibly some positives. I will keep going another month.

Helpful?
Kayla M.South Carolina
Verified buyer
★★★★★

I take this as directed every morning and have seen a real improvement in my focus and how long I can stay locked in on a task at work. I would recommend it.

Helpful?
AnonymousMassachusetts
Verified buyer
★★★★

Strong for me at two capsules. I was very awake but a little anxious feeling. Backed down to one capsule and that is plenty. I would recommend starting with one and seeing how you do.

Helpful?
Bradley W.Maryland
Verified buyer
★★★

A month on this and I did feel an energy lift but I also got lightheaded by the late afternoon a few times. Could just be me, everyones body is different. The brand is solid, I take a few of their other supplements without issue.

Helpful?
Brianna F.Wisconsin
Verified buyer
★★★★★

Two months in and I notice a real difference in my mood. Less foggy, more able to handle a long day at work without getting irritable in the evening.

Helpful?
Chris M.Indiana
Verified buyer
★★★★★

My doctor recommended I try this and I am glad I did. I feel more energized than I have in a long time.

Helpful?
Renee P.Nevada
Verified buyer
★★★★★

Best value for the dose Ive found. Other brands have fancier bottles but this one does what I need it to do.

Helpful?
Regina S.New Mexico
Verified buyer
★★★★

It started working for me within about two weeks and my brain felt sharper than it had in years. After a while my head was running so much that I had trouble winding down at night. Stopped taking it for that reason. Worked maybe a little too well for me.

Helpful?
Arturo R.Connecticut
Verified buyer
★★★★★

Helps me a lot with my physically demanding job. More endurance through the back half of my shifts than I had before.

Helpful?
Jack T.Iowa
Verified buyer
★★★★★

Gives me a real energy lift. Tip, be careful pairing this with coffee. One capsule and skipping the second coffee is plenty for me.

Helpful?
Marisol V.Kentucky
Verified buyer
★★★★★

A month and a half in. I really think it is helping with both energy and how clear headed I feel through the day.

Helpful?
Nora H.Utah
Verified buyer
★★★★★

My doctor recommended this when I told her I was dragging through my days. She said she takes it herself and loves the energy. I have noticed a difference too.

Helpful?
Gilbert L.Rhode Island
Verified buyer
★★★★

This combined with my other supplements is slowly helping with body composition. Not magic but pulling in the right direction.

Helpful?
Daniel H.Mississippi
Verified buyer
★★★★★

I have steady energy all day long when I take this. Solid product.

Helpful?
Joann D.Vermont
Verified buyer
★★★

I might have fallen for the hype. Halfway through the bottle and I dont notice any difference in my energy. Nothing bad happening either so there is that.

Helpful?
Mary D.Alabama
Verified buyer
★★★★★

Works for me and the price is fair. Happy with my purchase.

Helpful?
Margot A.Delaware
Verified buyer
★★

I have tried a more expensive precursor version and a noticeable difference in mental clarity. For me this one is a step down even though the price is better.

Helpful?
Lillian J.Kansas
Verified buyer
★★★★★

Boosts my energy when I exercise. Worth the cost.

Helpful?
Anton P.Maine
Verified buyer
★★★★★

A few weeks in and Im impressed. Capsules are easy to swallow and I notice a subtle boost in my energy and focus. Nice addition to my daily routine.

Helpful?
Carmen R.New Jersey
Verified buyer
★★★★★

Recommended to me by my doctor. Started this and the change has been real, feel much more re-energized.

Helpful?
Quinn L.Hawaii
Verified buyer
★★

Three weeks on this and very little to show for it. Disappointed.

Helpful?
Tony G.Nebraska
Verified buyer
★★★★★

Took about a week to kick in but the energy I have now is on a level I have not felt in a long time. No afternoon crash either.

Helpful?

Questions?
We're here to help.

NAD+ levels rise within the first 2 weeks. Energy and recovery effects show up at 2 to 4 weeks. Mental clarity follows at 4 to 8 weeks. Cellular benefits compound over 8 to 12 weeks of daily use.

NR (Nicotinamide Riboside) enters cells through a direct channel and converts to NAD+ inside. NMN must first convert to NR before being absorbed. NR has a more efficient route and a longer track record in published clinical research. Both work, but NR has the cleaner data.

NR raises NAD+, but NAD+ on its own doesn't drive cellular repair. Sirtuins do, and they require activation. Trans-Resveratrol activates sirtuins, which then consume NAD+ to do their work. Take NR alone and you raise the fuel. Pair it with Trans-Resveratrol and you start the engine.

Two capsules in the morning with food that contains some fat. Resveratrol and quercetin absorb better with fat, so breakfast with eggs, avocado, or another fat source significantly improves absorption.

500mg sits in the clinical range used in published NR research. Most low cost NR products ship 100 to 250mg, which falls below the dose where measurable NAD+ increases have been documented in clinical trials.

NR and the supporting compounds are tolerated well by most users. Mild flushing or GI discomfort can happen rarely. Talk to a healthcare provider if you take blood thinners, blood pressure medication, or have an existing medical condition. Not for use during pregnancy or nursing.

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Orders ship the next business day from our facility. Free insured shipping on orders over $100. USPS tracking sent by email once the label is generated.

Yes. Vegan capsules. Gluten-free. Non-GMO. Made in a GMP-certified facility in the USA. Each batch is third party tested for heavy metals, microbials, and identity.